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Sep 2026

The Delivery Strategies for PROTAC.

Yi-Jing Dang, Ze-Li Long, Jing Gao et al. · 0 citations
Review Open access Sep 2026

Molecular design and delivery of extracellular and membrane protein degradation chimeras.

Extracellular and membrane-associated proteins constitute a substantial therapeutic target space that remains largely inaccessible to intracellular degradation strategies based on the ubiquitin-proteasome system. Membrane and extracellular targeted protein degradation (meTPD) addresses this limitation by coupling targe...

Shu-Tong Lin, Hui-Ling Zhou, Jia-Yan Qiu et al. · 0 citations
Review Jul 2026

The design of activatable photosensitizers and applications in precision immunomodulation.

This review systematically elaborates on the molecular design principles of activatable photosensitizers and their recent advances in precise immunomodulation for cancer therapy, and delves into the underlying mechanisms by which activatable photosensitizers synergistically potentiate anti-tumor immune responses.

Mengzhen Wang, Yuan Huang, Fangmin Chen et al. · 0 citations

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