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Open access Oct 2026

Single-cell analyses reveal lymph node-tumor ecosystem remodeling during lymph node metastasis of gastric cancer.

Gastric cancer (GC) is a highly aggressive malignancy with a strong propensity for lymph node metastasis. To characterize the metastatic ecosystem, we perform integrated single-cell transcriptomic and T cell receptor profiling of 156,871 cells from 30 primary tumors and matched sentinel lymph nodes (SLNs), spanning non...

Zhi Zheng, Yu-Xi Zhang, Zi-Meng Wang et al. · 0 citations
Review Open access Jul 2026

Efficacy of gut-brain neuromodulators in functional esophageal disorders: a systematic review.

BACKGROUND Patients with functional esophageal disorders exhibit symptoms such as chest pain, heartburn, dysphagia, globus sensation, or reflux hypersensitivity in the absence of structural abnormalities. This is characterized by dysregulated gut-brain interactions and visceral hypersensitivity. METHODS A systematic...

Zimeng Wang, Zhi Zheng, Xi-Cheng Wei et al. · 0 citations

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