Author

Zhi-You Yang

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Open access Sep 2026

Fucus vesiculosus-Derived Fucoidan Mitigates Recognition Memory Deficits in Association with Modulation of the Microbiota–Gut–Brain Axis in Adenine-Induced Chronic Kidney Disease Mice

Chronic kidney disease (CKD) induces systemic oxidative stress and inflammation, leading to secondary cognitive impairment. The mechanisms by which marine-derived fucoidan exerts neuroprotection remain incompletely understood. Here we show that oral administration of Fucus vesiculosus-derived fucoidan improved object-r...

Xiao-Bo Kang, Zhi-You Yang, Zhihui Ma et al. · Marine Drugs · 1 citation

Review Sep 2026

Phytocannabinoid cannabidiol (CBD) in neurodegenerative diseases: From polypharmacology to drug development.

Cannabidiol (CBD) is a non-intoxicating phytocannabinoid that has attracted interest as a multi-target neurotherapeutic candidate for neurodegenerative diseases. CBD is a lipophilic terpenophenolic chemotype whose phenolic redox chemistry, membrane partitioning, cytochrome P450-mediated metabolism, and formulation-depe...

Bing-Xing Zhang, Jiang Nan, Yun-Fei Zhang et al. · European journal of medicina... · 0 citations

Open access Jul 2026

Sarsasapogenin Improves Pathological Phenotypes in MPTP/MPP+-Induced Parkinson's Disease Models: Synergistic Actions of Neurite Outgrowth, Neurotransmitter Modulation, and Anti-Inflammation.

Sarsasapogenin exerts comprehensive neuroprotective effects in preclinical PD models via synergistic modulation of dopaminergic neuronal survival, neurotransmitter balance, inflammatory inhibition, and neurite outgrowth.

Wen-Di Deng, Jin-Feng Hong, Weixia Li et al. · Journal of Integrative Neuro... · 0 citations