Author

Zhi-Yong Liang

2 papers indexed here

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Open access Aug 2026

Enhancer Collapse Dictates PKHD1 Silencing and Centrosome-Mediated Chromosomal Instability and Metastasis in Clear Cell Renal Cell Carcinoma.

Chromosomal instability (CIN) drives clear cell renal cell carcinoma (ccRCC) progression, yet its upstream triggers remain elusive. To identify key drivers governing renal genomic integrity, we integrated machine learning-driven screening with Mendelian randomization analysis to prioritize candidates associated with bo...

Yue-Yang Wang, Lingling Wang, Jingwen Deng et al. · Experimental Cell Research · 0 citations

Open access Jul 2026

AI-driven tumor heterogeneity quantification and survival prediction in pancreatic ductal adenocarcinoma.

An interpretable and high-performing artificial intelligence framework for quantitative modeling of PDAC was established, and Objective characterization of tumor heterogeneity and accurate postoperative survival prediction are enabled, with potential value for personalized management in PDAC.

Li-Zhi Shao, Xin-Yi Ke, Yun Wang et al. · npj Digital Medicine · 1 citation