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Learning-enhanced hybrid planar-SPECT dosimetry for voxel-level Monte Carlo dose estimation in radionuclide therapy
Objective. Quantitative imaging-based dosimetry is essential for optimizing [177Lu]Lu-DOTATATE peptide receptor radionuclide therapy, yet full multi-time-point (MTP) SPECT/CT is difficult to implement in routine clinical practice. This study proposes a hybrid planar-SPECT framework for organ-level time-integrated activ...