Zhi-Xue Shen

A bioinspired adhesive hydrogel promotes bone regeneration through osteoimmunomodulation and angiogenic-osteogenic coupling.

Delayed bone defect repair is mainly attributed to insufficient mechanical interlocking between the material and host tissue, excessive inflammation, and inadequate vascularization. Here, we report a bioinspired organic-inorganic composite hydrogel (OP/bECM@Z) developed based on the biphasic structure of native bone. P...