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Zhi-Wu Zeng

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Open access Sep 2026

Gut microbiota dysbiosis aggravates liver injury in acute-on-chronic liver failure through D-lactate accumulation

Introduction Acute-on-chronic liver failure (ACLF) is a life-threatening condition arising from the abrupt worsening of pre-existing chronic liver disease, typically accompanied by multi-organ failure and markedly elevated short-term mortality. Gut microbiota dysbiosis is frequently observed in patients with ACLF, yet...

Zhi-Wu Zeng, Li-Ning Xu, Ming-Qing Yang et al. · 0 citations

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