Sep 2026
HCE6-mediated photodynamic therapy induces hepatocellular carcinoma cell death via inhibition of autophagic flux.
Porphyrin derivatives are potential candidates for photodynamic therapy against cancer. In this study, hydrophilic chlorin e6 trisodium salt (HCE6) was selected for treatment of hepatocellular carcinoma (HCC). SK-hep1 cells and a xenograft mouse model were used to investigate the antitumor efficacy and the autophagic m...
Xin Jiang, Ke-Yi Zhou, Xin-Tian Huang et al.
· Journal of materials chemist... · 0 citations