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Zhi-Kun Wang

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Open access Sep 2026

Metabolic Targeting of SREBP1 Reprograms the Obesity-Driven Ascites Immune Microenvironment and Enhances Chemotherapy Response in Obesity-Associated Ovarian Cancer

The results demonstrate significantly improved therapeutic response, corresponding changes in intra-tumoral adipocytes, and reprogramming of the obesity-driven ascites immune microenvironment, and highlight metabolic targeting as a strategy to improve therapeutic outcomes in obesity-associated ovarian cancer.

Jing Yang, Tyvette S. Hilliard, Yue-Ying Liu et al. · 0 citations

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