Zhi-Hong Zheng

WSSV exploits host glycolytic reprogramming to promote hemocyanin lactylation and enhance cell-associated WSSV levels in shrimp.

White spot syndrome virus (WSSV) is a major pathogen in shrimp aquaculture, yet how virus-induced metabolic rewiring alters immune effector function remains poorly understood. Here, we show that WSSV infection in Litopenaeus vannamei induces a Warburg-like metabolic shift characterized by increased glucose uptake, tran...