Atherosclerosis (AS) is a chronic inflammatory disease in which vascular smooth muscle cell (VSMC) pyroptosis and foam cell formation play critical roles. Curcumin has anti-atherosclerotic effects, but its molecular mechanism remains unclear. In this study, we investigated whether and how curcumin regulates VSMC pyropt...
Lin Xie, Xuan Zeng, Yun-Xian Wu et al.· International Immunopharmaco...· 0 citations
Introduction Granulomatous prostatitis (GP) is a relatively uncommon disorder, accounting for approximately 0. 8% to 1.0% of all benign inflammatory prostatic conditions. Xanthogranulomatous prostatitis (XGP) is an exceptionally rare subtype of GP, with only a limited number of cases documented in the medical literatur...
Ming-Feng Ji, Yi-Hao Chen, Hao-Xuan Feng et al.· Frontiers in Medicine· 0 citations
These findings identify AR/ZNF217/PROM2 signaling as a central determinant of ferroptotic vulnerability in prostate cancer and suggest that targeting this pathway may enhance sensitivity to AR inhibition, providing a molecular rationale for combination therapy in castration-resistant prostate cancer.