Author

Zhi‐Hang Wu

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Sep 2026

POLE2 of tumor cells promotes OPN secretion based on PCLAF to drive M2 macrophage polarization in clear cell renal cell carcinoma.

A comprehensive NFATc2/POLE2/PCLAF signaling axis that promotes ccRCC progression via OPN-mediated M2 macrophage polarization, providing a solid rationale and potential therapeutic targets for developing novel immunocombination therapies is unveiled.

An-Rui Li, Jing-Wen Xu, Zhi-Hang Wu et al. · Cancer Gene Therapy · 0 citations

Jul 2026

Phytochemical and anti-inflammatory profiling of Amomum maximum Roxb. Fruits reveal undescribed diarylheptanoids and labdane diterpenoids.

It is demonstrated that diarylheptanoids are the major anti-inflammatory components in A. maximum fruits, which not only validates the ethnopharmacological use of this herb, but also provides new anti-inflammatory agents derived from natural products.

Jinna Zhao, Shu-Fei Yu, Yan-Jun Ding et al. · Fitoterapia · 0 citations