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Zhi-Feng Shao

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Open access Aug 2026

MacroH2A2-Enriched Domains Are Largely Stable Across the Cell Cycle but Focally Displaced at Mitotic Regulatory Elements

The macroH2A variants mH2A1 and mH2A2 are structurally similar but not identical. Our previous study demonstrated that mH2A1 is reloaded during cell-cycle progression, but whether mH2A2 follows similar dynamics has remained unclear. Here, we used native ChIP-seq in synchronized Huh-7 cells to profile both variants at G...

Yong-Zhuo Deng, Ze-Qian Xu, Le Zhang et al. · 0 citations
#protein folding Aug 2026

Direct Visualization of Orientation Competition in Protein Epitaxial Crystallization.

In situ atomic force microscopy is used to reveal the two-dimensional crystallization dynamics of streptavidin on muscovite mica with single-molecule resolution, establishing a paradigm of domain coarsening in biomolecular epitaxy, providing a solid foundation for the rational design of functional bio-nano interfaces.

Yuhui Wei, D. Czajkowsky, Wei Zheng et al. · 0 citations

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