Zhi-Fang Fu

Aging-associated loss of CPEB4 impairs mitochondrial adaptation and promotes stress-induced senescence in alveolar type II cells.

Aging is associated with impaired lung repair and increased susceptibility to injury, yet the mechanisms underlying age-associated dysfunction of alveolar type II (AT2) cells remain poorly understood. Although cellular senescence is a hallmark of aging, emerging evidence suggests that aging is also characterized by pro...