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Zhi-De Zhu

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Open access Oct 2026

Mechanism of luteolin in treating chronic heart failure by regulating HIF-1 signaling pathway-mediated mitochondrial damage to inhibit cardiomyocyte apoptosis

Background Chronic heart failure (CHF) is a systemic cardiovascular disease characterized by an extremely poor prognosis. Luteolin demonstrates promising therapeutic potential in the prevention and management of CHF. This study aims to explore the mechanism by which luteolin ameliorates CHF through mitigating mitochond...

Wei-Qi Shi, Zhi-De Zhu, Jun-Shen Lu et al. · 0 citations

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