Aug 2026
Bimetallic modified titanium carbide nanoparticles loaded with transcription factor E3 ameliorate intervertebral disc degeneration by eliminating reactive oxygen species and promoting autophagic flux.
In a needle puncture-induced IVDD rat model, intra-disc injection of Ti3C2@PtAu@TFE3 alleviated structural deterioration and prevented ECM destruction and the potential application of Ti3C2@PtAu@TFE3 against IVDD is demonstrated.
Jianle Wang, Tianyou Gao, Yingfeng Su et al.
· International Journal of Bio... · 0 citations