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Zheng-Yuan Zhai

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Dec 2026

High CLA-producing Lactiplantibacillus plantarum MNN1 alleviates irritable bowel syndrome through activation of intestinal PPARα signaling pathway.

Irritable bowel syndrome (IBS) is a common gut-brain axis disorder characterized by visceral hypersensitivity, abdominal pain, and anxiety. Although probiotics have emerged as a promising strategy for IBS management, the specific metabolite-driven mechanisms and their role in gut-brain axis modulation remain largely un...

Xiao-Yue Bai, Yi-Zhi Jing, Yue Wang et al. · 0 citations
Open access Sep 2026

Transplantation of Elderly Human Gut Microbiota Into Pigs Reprograms Intestinal Barrier Function, Plasma Metabolome, and Gut Mucosal Transcriptomic Landscape

The gut microbiota plays a pivotal role in maintaining intestinal homeostasis and regulating host metabolism, yet its composition and function undergo substantial alterations with aging. However, the relationship between age‐associated microbial changes and host intestinal physiology remains not fully elucidated. Here,...

Jia-Xin Wang, Ling-Yu Li, Li-Hua Mei et al. · 0 citations
Open access Sep 2026

Science-Push and Market-Pull in Hydrogen Technology Collaborative Innovation System: A Tripartite Evolutionary Game Analysis

Hydrogen innovation requires coordination across scientific research, engineering development, infrastructure deployment, market application, and public governance. However, heterogeneous incentives can destabilize collaborative participation even under strong policy support. This study examines how science-push and ma...

Ya-Dong Wang, Ming-Jie Wang, Qing-Ting Cai et al. · 0 citations
Jul 2026

Engineering glucose uptake for enhanced production of L-tyrosine in Bacillus amyloliquefaciens.

L-Tyrosine is an important aromatic amino acid widely used in dietary supplements and as a precursor for high-value food ingredients. Microbial fermentation presents a sustainable and green production route, but achieving high titers remains challenging due to incomplete understanding of metabolic regulation. In this s...

Ziyue Zhao, Anying Ji, Xue-Tuan Wei et al. · 0 citations

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