Author

Zheng-Yang Zhou

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Open access Sep 2026

Mediating effect of pro-inflammatory cytokines in the association between depression, anxiety, and cardiometabolic disorders in a multiethnic US population

Neuroinflammation is associated with depression and anxiety risk, both of which demonstrate a bilateral relationship with cardiometabolic disorders. Systemic inflammation was also commonly described in patients with cardiometabolic disorders. It is, thus, unclear whether pro-inflammatory cytokines might statistically m...

Asma Hallab, S. O'Bryant, Kristine Yaffe et al. · Scientific Reports · 0 citations

Sep 2026

APOE:RAAS epistasis as a population specific risk factor for cognitive impairment and cardiovascular health.

BackgroundThe strongest genetic risk factor for development of Alzheimer's disease (AD) and/or AD-related dementias is the ε4 allele in the apolipoprotein E (APOE) gene, though the frequency and impact of this variant on cognitive decline can vary across populations. Vascular and metabolic disorders (e.g., hypertension...

Amanda E. Tucker, Robert C. Barber, Zheng-Yang Zhou et al. · Journal of Alzheimer's Disea... · 0 citations