Open access
Jul 2026
MLKL confers ferroptosis resistance in colorectal cancer cells via impaired ESCRT-III-mediated membrane repair.
BACKGROUND Ferroptosis resistance is a major challenge in cancer therapy, contributing to poor prognosis and unsatisfactory treatment outcomes. Thus, identifying key regulators of ferroptosis is essential for developing strategies to overcome this limitation. Mixed lineage kinase domain-like protein (MLKL) is well esta...
Sasiprapa Sonkaew, Nattaya Duangthim, C. Butkinaree et al.
· Biology Direct · 0 citations