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Author

Zhen Yu

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Open access Aug 2026

Targeted therapy of colon cancer with aptamer-functionalized albumin nanoparticles loaded with disulfiram

Chemotherapy remains the primary treatment for most patients with metastatic colorectal cancer (mCRC), yet its efficacy is often limited by severe adverse effects. Drug repurposing offers a promising strategy to accelerate oncology drug development. Disulfiram (DSF), a licensed anti-alcoholism agent, has demonstrated b...

Y. An, Zhen Yu, Ting Li et al. · 0 citations
#protein folding Open access Aug 2026

Integrated multi-omics analysis of metabolomics and proteomics uncovers dysregulated amino acid metabolism in HCC metastasis

Widespread disturbances in amino acid metabolism were identified via untargeted metabolomics in HCC patients with metastasis, closely governing inflammation-related metabolic remodeling and oxidative stress responses.

Jing Wu, Jin Wang, Zhen Yu et al. · 0 citations

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