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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Zhen Shao

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Aug 2026

GDF15 ameliorates inflammatory arthritis-associated bone destruction and pain through inhibition of osteoclastogenesis and modulation of osteoclast-derived Netrin-1/CGRP+ nerve remodeling.

Findings identify GDF15 as an endogenous protective factor in inflammatory arthritis that limits osteoclastogenesis, bone destruction, and pain-related nerve remodeling, highlighting its potential as a therapeutic target for RA.

Li-Juan Mao, Hao-Ran Huang, Zhen Shao et al. · 0 citations

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