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Author

Zhen-Nian Xie

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Sep 2026

A 4-Arm polyethylene-glycol-based multivalent galactoside disrupts Pseudomonas aeruginosa biofilm and restores antibiotic susceptibility.

Results indicate that 4-Arm-PEG-Gal significantly disrupts mature biofilm and is specifically recognized by the lectin LecA, and compared to the use of antibiotics alone, the combination of 4-Arm-PEG-Gal and TOB reduces antibiotic usage by 75% and additionally eradicates 73% of the bacteria within the biofilm.

Chen-Xiao Wan, Xiaoyan Ju, Mei-Yun Ma et al. · 0 citations

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