Zhen-Liang Zhang

A label-free fluorescent sensor for miR-21 based on sequentially coupled CHA–HCR dual-stage amplification and synergistic signal regulation by graphene oxide and SYBR Green I

MicroRNAs (miRNAs) are promising biomarkers for cancer diagnosis, and their sensitive and accurate detection is important for early cancer diagnosis. However, achieving sensitive miRNA detection and logic analysis while maintaining a simple workflow remains challenging. In this study, catalytic hairpin assembly (CHA) a...