Author

Zhen-Liang Wen

2 papers indexed here

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Open access Aug 2026

Associations of Heart Rate Trajectories with Mortality and AKI Occurrence in Septic Patients: A Retrospective Study from MIMIC-IV and eICU Databases

Background: Abnormal heart rate is a common early manifestation of sepsis, but the association of the dynamic changes with clinical outcomes remains unclear. This study aimed to investigate the relationship between dynamic heart rate trajectories and 28-day mortality as well as acute kidney injury (AKI) in patients wit...

Yang Yang, Hang-Xiang Du, Zhen-Liang Wen et al. · Journal of Clinical Medicine · 0 citations

Open access Sep 2026

mtROS-NF-κB signaling supports ILC3 function and survival during sepsis-induced intestinal injury

Findings identify a mitochondria-associated ROS-NF-κB program that sustains protective cytokine production and survival in residual intestinal ILC3s during sepsis, although it is insufficient to prevent ongoing ILC3 loss and intestinal injury.

Li-Min Chen, Hao-Cheng Zhang, Si-Si Huang et al. · Frontiers in Immunology · 0 citations