Polydopamine-assisted architecture-enabled local delivery of miR-34a-loaded M1 macrophage extracellular vesicles and curcumin from an injectable thermogelling hydrogel for triple-negative breast cancer
Triple-negative breast cancer (TNBC) remains difficult to treat because of its aggressive phenotype, limited targetable pathways, and the need for local delivery systems that improve therapeutic retention without compromising cargo integrity. In this study, we engineered an injectable preorganized local dual-cargo de...