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Zhen-Hai Chen

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Open access Aug 2026

N-linked glycosylation of GETV envelope proteins affect viral infection and pathogenicity

ABSTRACT Getah virus (GETV) is an emerging mosquito-borne pathogen with a broad host range, posing a significant threat to livestock and public health. Although putative N-linked glycosylation sites on its envelope proteins have been reported, their precise functional roles remain uncharacterized. In this study, tunica...

Hui Meng, Tian-Yi Wang, Chun-Xiao Mou et al. · 0 citations
Sep 2026

SADS-CoV Nsp1 hijacks proteasomal subunits to degrade IRF1.

These findings uncover a new mechanism where SADS-CoV Nsp1 exploits the proteasome to degrade IRF1, countering IFN-III responses, and the conserved role of coronavirus Nsp1 in immune evasion.

Ying-Jie Xiang, Qin-Yuan Zhu, Yue Cheng et al. · 0 citations
Open access Aug 2026

Characterization and pathogenicity of single-farm-isolated PRRSV 1 and PRRSV 2 strain in China

The evidence of PRRSV 1 and PRRSV 2 concurrent circulation in the single sow farm in China is provided, which highlights the ongoing evolution of both Chinese PRRSV species and underscores the urgent need for enhanced surveillance and updated control strategies.

Zhendong Zhang, Di Gao, Zihe Wang et al. · 1 citation · ⚡1

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