Sep 2026
Controllable gene delivery via masked adeno-associated viral vectors.
Zhi-Ying Zeng, Li-Ying Chang, Jing-Jing Wang et al.
· Nature Materials · 0 citations
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Sep 2026
Delivery of CAR T Cells in a Magnesium-Functionated Hydrogel Boosts Peritoneal Metastasis Treatment.
Chimeric antigen receptor (CAR) T cells show limited efficacy in solid tumors due to suppressive factors in the tumor microenvironment. In this study, we identified extracellular magnesium (Mg2+) as a pharmacologically modulable regulator of CAR T activity. Mg2+ supplementation increased early activation and augmented...
Jun-Lin Li, Xu-Tao Liu, En Ren et al.
· ACS Applied Materials and In... · 0 citations
Aug 2026
Mussel-Inspired Membrane Encapsulation Strategy for Developing Long-Acting Glucose-Responsive Injectable Insulin Crystals.
This study presents a bioinspired membrane-enclosed strategy for developing long-acting and injectable formulations for hydrophilic drugs, and exhibits in vivo glucose-responsive insulin release, low risk of hypoglycemia, biodegradability, and high biocompatibility.
Jian-Chang Xu, Yanfang Wang, Jingyi Chen et al.
· Journal of the American Chem... · 0 citations
Review
Aug 2026
Artificial Intelligence for Drug Delivery.
An overview of the applications of AI in drug delivery is highlighted, focusing on AI-designed drug formulations, AI-driven prediction of ADMET properties, and AI-assisted drug delivery devices, which support the development of precision medicine.
Xinmin Yu, Xinyun Jiang, Tao Sheng et al.
· ACS Nano · 1 citation