Sep 2026
Triptolide enhances oxaliplatin sensitivity by suppressing the JAK2/STAT3 pathway in cancer cells.
BACKGROUND Liver cancer and lung cancer are major causes of cancer-related deaths worldwide. Oxaliplatin is a first-line chemotherapeutic agent, but its efficacy is often limited by acquired resistance. PURPOSE This study investigated whether triptolide (TPL), a bioactive compound derived from a traditional Chinese m...
Ruoxuan Lou, Gui-Qing Li, Ying Chen et al.
· Bioorganic chemistry (Print) · 0 citations