Author

Zhehao Zhang

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Open access Aug 2026

Immune Circuit Rewiring by HDAC Inhibition Enables Response to Dual Checkpoint Blockade in Metastatic Breast Cancer

Overall, this study identifies lymphoid and myeloid cell contributions to response to treatment with HDAC inhibitors and immune checkpoint blockade, providing a framework for discovering interactions driving responses in complex TMEs.

E. Gonzalez, J. Kreger, Ying-Tong Liu et al. · Cancer Research · 0 citations

Aug 2026

Impact of oncological biomarkers and clinical factors on survival outcomes in renal cell carcinoma with spinal metastasis: a retrospective analysis.

Immunohistochemical biomarkers, particularly CK7, AE1/AE3, CAM5.2, and EGFR, hold significant prognostic value in RCC spinal metastasis and can help stratify patients into high- and low-risk groups, and integrate into tree-based machine learning models provides interpretable data-driven decision tools to support person...

Joseph Rajasekaran, Xinlan Yang, A. Ghaith et al. · Journal of Neurosurgery : Sp... · 0 citations

Open access Jul 2026

A predictive tool incorporating frailty scores for perioperative risk assessment in patients with spinal metastasis: a national retrospective cohort study.

Integrating serum albumin, hematocrit, BMI, spinal region, and procedure type with frailty indices enhances risk stratification and informs surgical planning, preoperative optimization, and patient counseling in this vulnerable population of patients.

A. Ghaith, Xinlan Yang, Yazan Alasadi et al. · European spine journal · 0 citations