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Zhefeng Li

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Revealing Nanomedicine Design Principles for Efficient siRNA Delivery to the Central Nervous System

Abstract A series of polymer nanocapsules were designed and synthesized for non-viral siRNA delivery to the central nervous system via intracerebroventricular injection. Various factors can contribute to superior diffusion profiles. In this study, we find that size, charge, and morphology play important roles. Further,...

Zhe Tan, Supreet Kaur, Ritam Das et al. · 0 citations

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