Zhe-Wei Liang

B-351 Analytical Assessment of Fibronectin and Collagen I Fragment Biomarkers in Hypermobile Ehlers–Danlos Syndrome Using Immunoenrichment and LC–MS/MS

Hypermobile Ehlers–Danlos syndrome (hEDS) and hypermobility spectrum disorders (HSD) lack objective laboratory biomarkers, contributing to prolonged diagnostic delays and reliance on subjective clinical criteria. Ritelli et al. recently reported disease-associated ∼45–52 kDa fibronectin (FN) and type I collagen (...