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Author

Zhanzhan Li

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Review Open access Jul 2026

The cGAS–STING pathway in tumor immunity: dual roles, regulatory mechanisms, and precision therapeutic strategies

This review systematically elucidates the molecular activation mechanisms of the cGAS–STING pathway and its complex regulatory networks within tumors, with a particular focus on analyzing its dual functions—tumor immune surveillance versus tumor promotion—and the determining factors involved.

Haiyan Jiang, Zhanzhan Li, Xia Li et al. · 2 citations

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