Open access
Aug 2026
Lactobacillus acidophilus CICC 22162 alleviates sleep deprivation-induced cognitive impairment by remodeling gut microbiota and enhancing S-adenosylmethionine-mediated neuroimmune regulation
Introduction Sleep deprivation (SD) impairs cognitive function and induces hippocampal injury, yet the gut-derived mechanisms underlying these deficits remain incompletely understood. Methods Here, we established a mouse SD model using a modified multiple-platform water environment method and evaluated the effects of o...
Zhi-Qian Jiang, Zhuohan Zhang, Mengqi Shi et al.
· Frontiers in Microbiology · 0 citations