Open access
Aug 2026
Hepatic ChREBP Drives Cardiac Remodeling via ApoM Non-transcriptional Repression
This work identifies the hepatic ChREBP-SURF4-ApoM axis as a critical pathway in cardiac remodeling, and induction of hepatic ApoM secretion constitutes a new promising approach for treating cardiac remodeling and heart failure.
Shuang Zhang, Zhen-zhen Zhang, Zi-Han Ma et al.
· Circulation Research · 0 citations