Open access
Jul 2026
Immune evasion in locally advanced mismatch repair-deficient microsatellite instability-high colorectal cancer: Reduced T-cell infiltration and upregulation of epithelial IDO1 expression
The overall immunogenicity and prognostic relevance of immune markers in dMMR/MSI-H CRC depend on tumor stage, and immune profiling could be used for early-stage patient stratification and also suggests the potential benefit of early immunotherapeutic intervention.
Sabina Niyazova, C. Sers, H. Bläker et al.
· Oncoimmunology · 0 citations