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Author

Zeel Patel

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Open access Aug 2026

The protein disulfide isomerase P4HB/PDIA1 modulates cellular and misfolded forms of the prion protein

It is shown that stable knock-down of the protein disulfide isomerase P4HB in prion-susceptible CAD5 cells reduces PrPC levels and hinders the generation of protease-resistant PrP (PrPres) following infection with two different prion strains.

Genki Amano, H. Arshad, Zeel Patel et al. · 0 citations

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