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Ze-Shan Yang

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Open access Sep 2026

Matrine Suppresses Lung Cancer Progression via Dual Inhibition of CHEK1‐Mediated DNA Damage Repair and PI3K/AKT Survival Signaling

Lung cancer remains a leading cause of cancer‐related mortality worldwide, necessitating the development of novel therapeutic strategies. Matrine, a natural alkaloid derived from Sophora flavescens, has demonstrated broad antitumor properties, yet its underlying mechanisms, particularly concerning DNA damage response,...

Jiang-Hao Yu, Si-Yang Chen, Ting-Ting Hou et al. · 0 citations

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