MRI-Based Deep Learning Guides Multi-Omics Discovery of NBPF4 as a Therapeutic Target for Breast Cancer Lymph Node Metastasis
A multi-step approach that combines deep learning analysis of breast magnetic resonance imaging with several types of molecular data, including gene activity, protein levels, and genetic information, along with laboratory experiments establishes the NBPF4–MAPK–EMT axis as a key player in breast cancer metastasis and provides a general framework for turning imaging-based risk predictions into biological understanding and possible therapies.