Ze-Fang-Bi-Mo Zhao

Regulation of ferroptosis by inter-organellar metabolic signaling network

Ferroptosis is a form of regulated cell death driven by iron-dependent lipid peroxidation, and is therefore intrinsically coupled to cellular redox metabolism. Progression of ferroptosis is regulated by an integrated network of metabolic signaling pathways that involve inter-organellar communication. In this Review, we...