Author

Zahra Ebrahimi

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Open access Jul 2026

Affinity improvement of specific scFvs interacting with the Neisseria meningitidis factor H-binding protein: a molecular dynamics simulation approach and experimental study

Findings underscore affinity maturation as a powerful strategy for engineering high-affinity antibody fragments by integrating in silico maturation, molecular dynamics simulations, and experimental validation.

Bijan Ghazanfari, Zahra Ebrahimi, F. Yarian et al. · BMC Biotechnology · 0 citations