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Author

Z. Sobh

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Sep 2026

Chrysin-loaded casein nanoparticles protect against chlorfenapyr-induced renal injury through modulation of Nrf2/HO-1, NF-κB, and mitochondrial bioenergetics.

BACKGROUND Chlorfenapyr (CFP) is a pesticide that induces nephrotoxicity through oxidative stress, mitochondrial dysfunction, inflammation, and apoptosis. Casein nanoparticles may enhance the therapeutic efficacy of chrysin (CY). OBJECTIVE This study evaluated the protective effects of free CY and chrysin-loaded case...

Ahmad Najem Alshammari, Ayat B. Al-Ghafari, H. A. Al Doghaither et al. · 0 citations
Open access Jul 2026

Nano‐Rosmarinic Acid Protects Against Chlorfenapyr‐Induced Testicular Toxicity Through Modulation of NRF2/HO‐1 and NF‐κB/NLRP3 Signaling Pathways

Overall, RA‐loaded Chitosan nanoparticles provided superior protection against CFP‐induced testicular toxicity compared with crude RA, highlighting the potential of nanoformulation strategies to enhance RA's biological efficacy.

Ahmad Najem Alshammari, Ayat B. Al-Ghafari, H. A. Al Doghaither et al. · 0 citations

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