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Author

Z. Nikoloski

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Review Open access Aug 2026

Machine learning for mechanistic modeling of plant metabolic pathways.

Advances in computational power and structured representation of biochemical knowledge have fostered the development and use of models of plant metabolic pathways of increasing complexity. These advances have pointed out knowledge gaps about parameters inherent to these models and the need for large-scale data sets to...

Philipp Wendering, Z. Nikoloski · 0 citations
Open access Jul 2026

A hybrid machine learning and enzyme-constrained metabolic model for ab initio prediction of proteome reallocation

High expression of heterologous proteins in microbial cell factories frequently triggers a severe burden due to reallocation of finite cellular proteome. Conventional constraint-based models struggle to predict these resource shifts ab initio without relying on condition-specific omics data. To bridge this gap, we deve...

E. Motamedian, Z. Nikoloski · 0 citations

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