Open access
Oct 2026
PTPN2 sustains non-canonical inflammasome activation and shapes the inflammatory response to sepsis
The innate immune system relies on pattern recognition receptors to recognize and detect pathogens. Gram-negative bacteria release LPS-rich outer membrane vesicles (LPS-OMVs), which activate PRRs, trigger inflammation at distant sites and contribute to systemic inflammatory conditions like sepsis. Inflammasomes, ce...
Bianca Colalillo, Isabelle Aubry, Philippe Aumont et al.
· Cellular and Molecular Life... · 0 citations