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Z. Mardani

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Open access Sep 2026

Design and synthesis of metronidazole-substituted dihydropyrimidinones with biological evaluation and molecular docking studies

Metronidazole is a well-known Nitroimidazole drug with comprehensive antibacterial action. In this study, a series of novel Metronidazole-substituted 3,4-dihydropyrimidinones ( 3a–3j ) were synthesized via a modified Biginelli reaction to explore their potential as antibacterial agents. The newly synthesized comp...

Mojtaba Nouri, K. A. Dilmaghani, Z. Mardani · 0 citations

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