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Z. Ismail

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Open access Oct 2026

White matter hyperintensities moderate neuropsychiatric response to N-acetylcysteine and exercise therapy in vascular mild cognitive impairment.

BackgroundVascular mild cognitive impairment (vaMCI) is frequently accompanied by neuropsychiatric symptoms (NPS), particularly apathy, which are associated with white matter hyperintensities (WMH). N-acetylcysteine (NAC) combined with exercise may provide neuroprotective benefits.ObjectiveWe hypothesized that baseline...

Ethan Mah, D. Gallagher, Ye-Jin Kang et al. · 0 citations
Open access Aug 2026

Associations Between Cerebral Amyloid Angiopathy, Cognitive Impairment, and Depressive Symptoms

Background and Objectives Cerebral amyloid angiopathy (CAA) is associated with intracerebral hemorrhage, cognitive decline, and dementia. We examined (1) associations between CAA, cognitive impairment, and depressive symptoms; (2) whether depressive symptoms mediate the relationship between CAA and cognition; and (3) w...

Nikita Nukala, Ryan T. Muir, Andrew E. Beaudin et al. · 0 citations
Open access Jul 2026

Associations among mild behavioral impairment, cognition, and brain pathology in preclinical autosomal dominant Alzheimer's disease

It is revealed that mild behavioral impairment symptoms may emerge before cognitive decline in ADAD and supports the MBI‐C as a tool for detecting early behavioral changes linked to AD pathology and identifying at‐risk individuals for clinical trials and early intervention.

Catarina Tristão-Pereira, D. Vásquez, Jorge Alcina et al. · 1 citation

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