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Open access 2026

Histological and ultrastructural characteristics of the atrial appendages in atrial fibrillation

Introduction. Atrial fibrillation is one of the commonest forms of arrhythmia in clinical practice, posing a risk of thromboembolism affecting vital organs. Removal of the atrial appendages during cardiac surgery prevents thrombus formation and minimizes the risk of complications. The histological and ultrastructural b...

N. Gutyrchik, L. Kakturskiy, L. Mikhaleva et al. · 0 citations
Open access Sep 2026

Systemic–local immune remodeling in colorectal cancer: CD14+ cell-derived cytokine responsiveness, mucosal immune-cell organization, and exploratory metastasis-associated patterns

Background Immune regulatory networks contribute to colorectal cancer (CRC) progression, but most clinical studies focus on tissue immune-cell abundance or static inflammatory mediators. We investigated cytokine-response patterns in cultures derived from peripheral-blood CD14+ cells and local immune-cell composition in...

N. Shakhpazyan, L. Mikhaleva, N. Sadykhov et al. · 0 citations

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