Background/Objectives: The introduction of biomarker-guided therapies, including PI3K, AKT and PARP inhibitors as well as Selective Estrogen Receptor Degraders (SERDs), has expanded treatment options and delayed the need for chemotherapy in hormone receptor positive (HR+)/human epidermal growth factor receptor 2 negati...
C. Deutschmann, Matthias Filipovic, Dagmar Baha et al.· Cancers· 0 citations
Aging reshapes the human body at the cellular level, yet how cell identity, morphology, and spatial organization remodel across organs and the adult lifespan remains poorly mapped, at a scale and lifespan coverage that molecular spatial assays cannot yet reach. Treating the GTEx histopathology archive as a population-s...
Ernesto Abila, Yimin Zheng, Z. Bagó-Horváth et al.· bioRxiv· 0 citations
The findings support the feasibility of integrating both neoadjuvant treatment strategies into routine surgical practice; however, confirmation in larger prospective studies is warranted.
K. Wimmer, Katharina Kantner, R. Exner et al.· Frontiers in Medicine· 0 citations
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