Multisite Anodal Direct Current Stimulation Preserves Motor Function and Modulates Key Cellular Pathways in TDP-43 and SOD1 Mouse Models of Amyotrophic Lateral Sclerosis.
OBJECTIVES Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by degeneration of upper and lower motor neurons and disruption of normal motor network excitability. This study aimed to determine whether multi-site direct current stimulation (DCS) can modulate spinal motor circu...