The potential mechanism investigation of Lipocalin-2 in ferroptosis via the AMPK/SIRT3/FOXO3a axis in sepsis-associated acute kidney injury.
Sepsis-associated acute kidney injury (SA-AKI) is a common and severe complication of sepsis. Lipocalin-2 (LCN2), a biomarker for SA-AKI, has an undefined role and underlying molecular mechanism in regulating renal ferroptosis. This study aimed to elucidate the regulatory function and potential mechanism of LCN2 in ren...