Open access
Sep 2026
Size-dependent effect of site-specific polyethylene glycol modification of trastuzumab on the antibody functions
Polymer modification of antibodies has attracted attention for enhancing antibody functionality. Modification with polyethylene glycol (PEG) or biopolymers such as antibody-oligonucleotide conjugates has been investigated. Although direct effects at the modification site have been understood, distal effects of modifica...
Yuya Tsutsui, Hiroaki Ohno, Hiroki Akiba
· bioRxiv · 0 citations